Corona – Unfortunately not the crowning Glory

January 22nd, 2021 Innovation Insights

Chinese authorities reported the first death due to the coronavirus on 11th January 2020. Since then, more and more people, in more and more countries, have been dying every day from the respiratory disease known as Covid-19, and the numbers now reach into the thousands. The media reports, while governments appease and decides. But what is happening with research?

14 Research Fronts have been identified

A scientific analysis was performed using the Big Data analysis tool NETCULATOR. All scientific publications dealing with the topic of corona in the past 5 years were evaluated. The result is 14 different research fronts. Exemplary are the following research results:

Cluster 2 – Protein-based vaccine

Using the so-called MERS-CoV spike protein, it was possible to develop a recombinant influenza virus that could be used as a bivalent vaccine against H1N1pdm09 and MERS- CoV. This approach provides a basis for future vaccine development.

Cluster 10 – Research on macrophages

Certain macrophages, also called white blood cells or leukocytes, could protect the immune system from MERS-CoV and actively fight the virus. Research is being conducted to determine which type of immune cells would be particularly well suited. (e.g. leukocytes, such as TLR3, IL-1 beta or IFN-gamma).

Where in the world is research being done?

Currently, numerous organizations are conducting research on various aspects of the new coronavirus Sars-CoV-2. ALPORA has identified the 15 most important ones using NETCULATOR analysis. Initially, two institutions should be introduced:

NIAID National Institute of Allergy and Infectious Diseases

The NIAID National Institute of Allergy and Infectious Diseases specializes, among other things, in infectious diseases and vaccines, making the institute, which is based in Maryland, USA, predestined for research on coronaviruses. NIAID researchers could determine how SARS-CoV-2 enters cells within two weeks of the discovery of Covid-19.

WHO in Geneva

The World Health Organization (WHO) in Geneva, founded in 1948, is the United Nations’ coordinating agency for international public health. After an outbreak of the new coronavirus, WHO invited 300 experts from around the world to consult. They agreed on a list of research priorities in the fight against corona, including the development of diagnostic procedures, therapies, vaccines and, ultimately, the question of the origin of the virus to prevent further transmission from animals to humans. While it is considered certain that bats are at the beginning of the Sars-CoV-2 chain of infection toward humans because the virus shows 98 percent concordance with a coronavirus that infects bats. However, it is also quite certain that the bat soup that is allegedly consumed in Asia has nothing to do with it.

Innovation Insight Corona Virus 2020