ALPORA analyses scientific publications on CORONA

On 11 January 2020, Chinese authorities reported the first corona death. Since then, more and more people have been dying every day in more and more countries from the lung disease known as Covid-19, thousands more in the meantime. Therefore we asked ourselves two important questions. What has research done so far and what solutions are being worked on.

Download full article –  Innovation Insight Corona Virus 2020


14 Research fronts were identified

A scientific analysis was performed with the help of the big data analysis tool NETCULATOR. All scientific publications dealing with corona in the past 5 years were evaluated. The following research results are exemplary:

Cluster 2 – Protein-based vaccine
The MERS-CoV spike protein made it possible to develop a recombinant influenza virus that could be used as a bivalent vaccine against H1N1pdm09 and MERS-CoV. This approach provides a basis for the future development of vaccines.

Cluster 10 – Research on macrophages
Certain macrophages, also called white blood cells or leukocytes, could protect the immune system from MERS-CoV and actively fight the virus. Research is being conducted to determine which type of immune cells would be particularly suitable (e.g. leukocytes such as TLR3, IL-1 beta or IFN-gamma)

Where in the world is research being done?

Numerous organisations are currently conducting research on various aspects of the new coronavirus Sars-CoV-2, the 15 most important of which ALPORA has identified using NETCULATOR analysis. First of all, two institutions should be introduced:

NIAID National Institute of Allergy and Infectious Diseases
NIAID, the National Institute of Allergy and Infectious Diseases, counts infectious diseases and vaccines among its areas of expertise, making the Maryland, USA-based institute predestined for research into coronaviruses. NIAID researchers were able to determine how SARS-CoV-2 penetrates cells within two weeks of the discovery of Covid-19.

WHO in Genf
The World Health Organization (WHO) in Geneva, founded in 1948, is the United Nations coordinating authority for international public health. Following the outbreak of the new coronavirus, the WHO invited 300 experts from around the world for consultation. They agreed on a list of research priorities in the fight against Corona, including the development of diagnostic methods, therapies, vaccines and ultimately the question of the origin of the virus in order to prevent further transmission from animals to humans. It is certain that bats are at the beginning of the Sars-CoV-2 infection chain towards humans, as the virus exhibits a 98 percent correspondence with a coronavirus that affects bats. One thing we know for sure, however, is that the bat soup that is allegedly consumed in Asia has nothing to do with it.

Download full article –  Innovation Insight Corona Virus 2020